ABSTRACT
In the present study, 80 eyes of 40 patients with glaucoma, glaucoma suspect and ocular hypertension and visual acuity of 6/12 or better were studied. In these patients, contrast sensitivity measurements were done using Pelli-Robson contrast sensitivity chart and were related to visual field loss on perimetry using on Humphrey's visual field analyzer model in order to obtain mean deviation. Mean deviation in decibel was converted in log units (1 dB = 0.1 log units). In the present study, contrast sensitivity losses were noticed in only small number of patients as compared to mean deviation shown by these patients on perimetry. Although contrast sensitivity has proven to be an important test for the early detection/screening of the people for glaucoma in some studies, we observed that contrast sensitivity testing by means of Pelli- Robson chart was not as efficacious as automated threshold perimetry for early detection of glaucoma.
ABSTRACT
The present study evaluated safety and intraocular pressure lowering efficacy of ocular antiglaucoma drugs timolol maleate 0.5% and bimatoprost 0.03% as monotherapy for 12 weeks on 50 patients divided in two groups with established primary open angle glaucoma. Higher incidence (72%) was found in patients aged 50 years and above and 60% were males. In both the groups, significant fall in mean intraocular pressure was observed. The mean reduction in intraocular pressure was 29.9% for timolol group and 36% for bimatoprost group. Bimatoprost o.d. was statistically and clinically superior to timolol b.d. in lowering intraocular pressure.